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In CBL, we are curious about the best ways to combine human and physics-based knowledge with what we can learn from data. We advance the computational foundation for integrating human/physics knowledge with data-driven inference & learning, data-driven quantification and reduction of uncertainty in physics-based models, and deep learning of physics from data. We also explore applications in critical medical and healthcare challenges, especially those related to heart diseases. 

We collaborate with world leaders in clinical electrophysiology, imaging, mathematical modeling, and high performance computing. Our research is funded by the National Science Foundation and the National Institutes of Health, and recognized by the NSF CAREER Award and the Presidential Early Career Award for Scientists and Engineers (PECASE) to Dr. Linwei Wang.

Lab News

  • January 2024

    ICLR2024

    Maryam’s work on adaptive task sampling for meta-learning PINNs is accepted for publication ICLR 2024.

  • October 2023

    MICAAI2023

    Yubo’s work on developing PINN for cardiac electrophysiology simulation is accepted for publication in MICCAI 2023.

  • October 2023

    MICCAI23

    Nilesh’s work on developing an object-centric shape augmentation is accepted for publication in MICCAI 2023.

  • January 2023

    ICLR Acceptance 2023

    Xiajun and Ryan’s work on meta-learning to adapt heterogenous dynamics in time-series forecasting was accepted for publication as a spotlight in ICLR 2023.

Research

Integrating Domain Knowledge into Statistical Inference

Statistical inference and learning methods that allow the integration of rich domain knowledge, such as in the form of large-scale mechanistic simulation models, to improve inference from the data
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Electrocardiographic Imaging (ECGi)

Noninvasive computational imaging of electrical activity in the heart, for improving diagnosis, treatment, and prevention of cardiac arrhythmias and other heart diseases
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Learning Disentangled Representations

Learning to disentangle semantically-meaningful generative factors within the data, with a focus on learning inter-subject variations in clinical applications
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End-to-End Uncertainty Quantification

Data-driven personalization and uncertainty quantification of large-scale mechanistic models, with a focused application in personalized physiological modeling

Transferring Simulation to Real Data

Generalizing and transferring knowledge from computer simulation data to tasks where real data are expensive, difficult, or infeasible to obtain

Our People

Linwei Headshot in front of white board

 Linwei Wang, Ph.D.

Professor 
PhD Program of Computing and Information Sciences
Rochester Institute of Technology

Linwei and students in computer lab

The CBL is looking for creative, curious, and courageous minds to join the team.

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