Researcher Karin Wuertz-Kozak awarded over $250K from the Swiss National Science Foundation
Healthcare research will look at ways to modulate inflammation in treating back pain.
Degenerative disc disease (DDD) is the painful degeneration of the intervertebral disc due to dysregulated inflammation and the major cause of back pain. One of the primary regulators of inflammation are Toll-like receptors (TLRs), and microRNAs have shown to modulate TLR signaling. Karin will study the functional role of toll-like receptors associated with microRNAs in intervertebral disc pathophysiology. The project hopes to identify miRNA candidates that are associated with TLR2 and establish their functional role in degenerative disc disease.
For more information about this research, please visit the Tissue Regeneration & Mechanobiology Lab website
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