In Vitro Cellular Barrier Models

In Vitro Cellular Barrier Models

Tom Gaborski, Principal Investigator

We are using ultrathin membranes to enable development of novel co-culture and barrier models, as well as improved measurement and analysis of real-time barrier function. The ultrathin nature of the membranes not only enables improved physiological processes, but also optical, electrical and biochemical analysis of barrier properties. Furthermore, we can control and manipulate physical and biochemical cell-cell interactions by tuning membrane pore sizes and membrane thickness at the nanometer and micrometer scales.