Inverse Problems Seminar: Estimating electrical wave activity in the heart
Inverse Problems Seminar
Estimating electrical wave activity in the heart from its mechanical deformations
Dr. Niels Otani
Associate Professor
School of Mathematical Sciences, RIT
Abstract:
Electrical waves in the heart, called action potentials, are responsible for coordinating the heart’s mechanical pumping function. When abnormalities occur in the spatial and temporal patterns of these waves, irregular and sometimes life-threatening cardiac rhythms result. Thus, we believe that the ability to visualize these waves in both research and clinical settings is important in managing these arrhythmias. In this talk, I will describe our efforts to develop methods to “see” these waves, using mechanical deformations as input data. As this is an ill-posed inverse problem, I will focus on a Tikhonov regularization process, which operates in a Krylov-like subspace obtained from Lanczos bidiagonalization. Other approaches we have tried will also be discussed briefly.
Speaker Bio:
Niels Otani obtained his BA degree in Physics from the University of Chicago with degree requirements also satisfied for a BS in Mathematics. He has a PhD in Physics from the University of California, Berkeley. Originally a researcher in the area of plasma physics, Dr. Otani has spent the last 20+ years in the area of cardiac electrophysiology, where he has developed several mathematical theories and computer models of the dynamics of cardiac rhythm. Dr. Otani is currently an Associate Professor in the School of Mathematical Sciences at RIT.
Intended Audience:
Undergraduates, graduates, and experts. Those with interest in the topic.
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Event Snapshot
When and Where
Who
Open to the Public
Interpreter Requested?
No