Viet Le
Senior Lecturer
Department of Science and Mathematics
National Technical Institute for the Deaf
Viet Le
Senior Lecturer
Department of Science and Mathematics
National Technical Institute for the Deaf
Education
BS, Ph.D., Wichita State University
Select Scholarship
Journal Paper
Le, Viet Q, et al. "In Vitro Characterization of Dopaminergic Toxins: A Laboratory Exercise Suitable for a Senior Undergraduate Biochemistry Laboratory Curriculum." ACS Journal of Chemical Education. (2024): xxx-xxx. Print.
Le, Viet Q, et al. "Extracellular H+ Ions are a Novel Signal for Tyrosine Hydroxylase Activation in Catecholaminergic Cells." ACS Chemical Neuroscience 14. 10 (2023): 1774-1784. Print.
Mapa, Mapa, Viet Le, and Kandatege Wimalasena. "Characteristics of the Mitochondrial Uptake of MPP+, as Probed by the Fluorescent Mimic, 4’I-MPP+." PLoS One 13. 8 (2018): e0197946. Print.
Wimalasena, Nivanthika K., et al. "Gene Expression-Based Screen for Parkinson’s Disease Identifies GW8510 as a Neuroprotective Agent." ACS Chemical Neuroscience 7. 7 (2016): 857—863. Print.
Published Conference Proceedings
Steed, Tabitha, Darrell Gumbs, and Viet Le. "Identiication of Novel Sodium/Chloride-Independent and Calcium-sensitive MPP+ Uptake Pathway Present in Dopaminergic Cells." Proceedings of the 63rd Annual Student Research Symposium of the Rochester Section of the American Chemical Socieity. Ed. American Chemical Society. Brockport, NY: n.p., Web.
Le, Viet, Mapa Mapa, and Kandatege Wimalasena. "Fenamate Protects Against 1-methyl-4-phenylpyridinium-induced Apoptosis in Dopaminergic MN9D Cells." Proceedings of the Proceedings of the 256th National Meeting of the American Chemical Society. Ed. American Chemical Society. Boston, MA: n.p., 2018. Web.
Le, Viet, Mapa Mapa, and Kandatege Wimalasena. "Reverse transport of 1-methyl-4-phenylpyridinium (MPP+) is mediated by extracellular calcium in dopaminergic MN9D." Proceedings of the 253rd National Meeting of the American Chemical Society. Ed. American Chemical Society. San Fransico, CA: n.p., Print.
Le, Viet, Mapa Mapa, and Kandatege Wimalasena. "2-APB and CGP-37157 as Neuroprotective Agents Against the Toxicity and Uptake of 1-Methyl-4-Phenylpyridinium in Dopaminergic MN9D Cell." Proceedings of the Proceedings of the 254rd National Meeting of the American Chemical Society. Ed. American Chemical Society. Washington, DC: n.p., Web.
Le, Viet and Kandatege Wimalasena. "Novel Na+ -independent Ca2+/dopamine/ MPP+ Uptake System Is Present In Dopaminergic Cells." Proceedings of the 251th National Meeting of the American Chemical Society. San Diego, CA. 13, March 2016. Ed. American Chemical Society. San Diego, California: n.p., Web.
Le, Viet Q. and Kandatege Wimalasena. "The Role of Calcium In The Mechanism of N-methyl-4-phenylpyridirum (MPP+) Toxicity Toward Dopaminergic Cells." Proceedings of the 44th American Chemical Society Middle Atlantic Regional Meeting. Riverdale, NY. 11, June 2016. Ed. American Chemical Society. Riverdale, NY: n.p., Web.
Uninvited Presentations
Steed, Tabitha, Darrell Gumbs, and Viet Le. "Identiication of Novel Sodium/Chloride-Independent and Calcium-sensitive MPP+ Uptake Pathway Present in Dopaminergic Cells." NTID’s 3rd Annual Student Research Fair. NTID. Rochester, NY. 13 Apr. 2018. Poster Session.
Wright, Holly, Joanna Mari, and Viet Le. "Statistical Analysis of Amiloride and 4,4’-diisothiocyanostilbene-2,2’-disulfonic acid (DIDS) with Neuroprotective Properties in MN9D cells under acidosis condition." 2018 Undergraduate Research Symposium at RIT. Rochester Institute of Technology. Rochester, NY. 3 Aug. 2018. Poster Session.
Currently Teaching
NLST-171
Fundamentals of Chemistry I
3 Credits
This course is an introduction to the fundamental theories and principles of chemistry governing the structure and behavior of matter at the atomic and molecular levels. The language of chemistry including nomenclature and symbolic representation is presented. Computational strategies applied to stoichiometry, reaction analysis and solution preparation are practiced. Laboratory activities focus on precision and accuracy in the collection, analysis and interpretation of data. Chemical hygiene and safety procedures in the laboratory will be emphasized. Chemical nomenclature will be introduced and practiced. Stoichiometry, product prediction and balancing of chemical reactions will accompany wet-lab activities.
NLST-172
Fundamentals of Chemistry II
3 Credits
This course is an introduction to the concepts of kinetics and thermodynamics. Chemical equilibrium and rate constants will be presented and quantified. The ideal gas law will be explored. Mathematical models will be developed and computational strategies will be applied and practiced. Laboratory activities will supplement course themes. Chemical hygiene and safety procedures in the laboratory will be emphasized.
NLST-220
Analytical Chemistry
4 Credits
This course introduces quantitative analysis utilizing both gravimetric and volumetric techniques. Topics include volumetric preparation and analytical procedures, acid/base and electron transfer titrations and related computational methods, and gravimetric procedures and analyses. Standard laboratory notebook protocol will be introduced and practiced. Chemical hygiene protocol and safety procedures in the laboratory are emphasized.
NLST-230
Principles of Organic Chemistry
4 Credits
This course provides an introduction to the principles of organic chemistry. Topics include structure, nomenclature, and properties of carbon-containing molecules according to the various functional groups that are central to organic chemistry. Investigations involving chemical reactions, data collection, and qualitative and quantitative analyses provide a framework for laboratory activities. Chemical hygiene and safety procedures in the laboratory are emphasized.
NLST-235
Principles of Biochemistry
3 Credits
This course provides an introduction to the principles of biochemistry through a study of carbohydrates, lipids, amino acids, proteins, enzymes, and nucleic acids. The metabolic pathways that involve these systems will also be explored. Principles of general and organic chemistry will be emphasized through an examination of the structures, concepts, and reactions that are central to biologically important molecules.
NLST-240
Biotechnology I
3 Credits
This course prepares students to perform biotechnical applications in industry-specific fields of analysis. Standard methods, operating procedures, equipment/instrumentation, and protocols are introduced and reinforced. Topics include ethical issues in Biotechnology, DNA manipulation, protein analysis, tissue culture, and molecular diagnosis. Sampling, testing, and reporting in the field of biotechnology are covered.
NLST-245
Biotechnology II
3 Credits
This course prepares students to perform Biotechnology applications in industry, specifically as they relate to microorganisms, proteomics, and genomics. Topics include bacterial expression systems for production, purification and characterization of recombinant proteins. Study will include concepts of DNA manipulation/analysis and enzymology. Standard methods, operating procedures, and protocols are introduced and reinforced. Sampling, testing, and reporting in the fields of Biotechnology, microbiology, and molecular biology are covered.